- 44 total number
- Brasil (Belo Horizonte)
The most appearances by a nation in the CONMEBOL Copa América is 44, and was achieved by Uruguay, at Estádio Mineirão, in Belo Horizonte, Minas Gerais, Brazil, on 16 June 2019.
As of 2020, Uruguay has only missed one tournament in the CONMEBOL Copa América's 45 year history. Argentina is a close second with two appearances less.